The brachialis (also brachialis anticus or Casserio muscle) is a muscle in the upper arm that flexes the elbow. It lies beneath the biceps brachii, and makes up part of the floor of the region known as the cubital fossa (elbow pit). It originates from the anterior aspect of the distal humerus; it inserts onto the tuberosity of the ulna. It is innervated by the musculocutaneous nerve, and commonly also receives additional innervation from the radial nerve. The brachialis is the prime mover of elbow flexion generating about 50% more power than the biceps.

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